The PM has struggled since she was recently forced to make an embarrassing U-turn on plans to reform social care laid out in the party's manifesto.
Mrs May chose to stick to her decision not to take part, even though Labour Party leader Jeremy Corbyn announced earlier on Wednesday that he would be there.
Caroline Lucas, co-leader of the Green Party, said: "The first rule of leadership is to show up", adding: "You don't call a general election and say it's the most important election in her lifetime and then not even be bothered to come and debate the issues at stake".
So why didn't the ruling leader of the Conservative Party take part in the debate on Wednesday?
Although the remarks from viewers and other politicians was expected, what we didn't think we'd see is a U.S. television show involving themselves in the drama, with many being left amused when the official Twitter account for Netflix's political drama House of Cards trolling the Prime Minister.
"I think Amber Rudd did an excellent job", replied the Prime Minister.
"Thank you, Tim, for that pass", she told Mr Farron after his attack on her absent boss. In fact, Bake Off is on BBC2 next, why not make yourself a brew?
"Theresa May called this election because she is taking you for granted", Ms Leanne Wood, who heads Welsh nationalist party Plaid Cymru, said in her opening statement.
She's more interested in meeting the public: May says that the election is about meeting members of the public face-to-face, and that she would prefer to do that than attend debates.
May's rating for leadership and economic competence are ahead of Corbyn's, gauges that have a better track record of predicting the outcome than vote-share forecasts, according to Bloomberg.
"This prime minister is for turning but not for turning up". You are not worth Theresa May's time.