The motive for the attack is not known.
Russian Federation said the crash was caused by a bomb, and banned flights to Russian Federation from Egyptian airports in response.
The attacker has also since been arrested and is being questioned by police.
In that attack, gunmen riding a motorcycle opened fire on a security vehicle patrolling a Giza village near some of Egypt's oldest pyramids, the Interior Ministry and officials said.
The interior ministry said a day later that it had killed 14 alleged IS members in a raid on a training camp in the eastern province of Ismailiya.
Hurghada is one of Egypt's most popular beach resorts, especially with Ukrainians and European tourists.
The ministry said the man appeared to have accessed the hotel by swimming from a nearby public beach.
According to the information resource Al-Youm Al-Sabia with reference to representatives of security service reported that the offender transferred by the bodies of the Higher state security prosecution in Egypt.
There was no immediate claim of responsibility for Friday's stabbing. Previous attacks in Cairo have been claimed by Islamic State and by Hasm, a shadowy militant group thought to have been drawn from the ranks of the banned Muslim Brotherhood. Last week, 23 army personnel were killed in an attack that targeted army checkpoint in the North Sinai city of Rafah.
The suspect was said to have specifically targeted woman and tourists and was reportedly heard shouting: 'Stay away, I don't want Egyptians'.
Earlier this week, the ministry said police had killed six IS militants in a shootout in southern Egypt.
The jihadists have threatened to carry out further attacks on Christians, who make up about 10 percent of Egypt's 90 million people.