Chelsea were held to a 1-1 draw on Tuesday night which let AS Roma overtake them in the table.
Teams from the same group or country can not be drawn against each other, limiting some of the potential match-ups in the first knockout stage.
Find out why Chelsea supporters could be anxious ahead of Monday's Champions League round of 16 draw... "At this stage of the competition, those that qualify are top teams - you can't dodge anyone too much - but I hope the draw is a good one for us".
Marcus Rashford ensured Manchester United progressed to the last 16 as group winners as they came from behind to see off CSKA Moscow.
And when asked whether Atletico's early Champions League exit following a 1-1 draw with Chelsea would further grease the wheels for an imminent exit, Simeone was quick to play down any talk of a move away for the 26-year-old.
Conte reckons it will take a special effort to be crowned Europe's top dog, despite beating the odds in the Premier League last season.
With European heavyweights like Bayern Munich, Chelsea, Real Madrid and Juventus in pot two, there are guaranteed to be some blockbuster clashes in the second round. The number of English sides finishing at the top of their group, means that Chelsea only have a few options when it comes round to the draw.
"We have to go game by game and try to do our best", said boss Conte. As a result of these restrictions, the Blues would only be able to draw three teams in the round of 16 - Barcelona, Paris Saint-Germain or Besiktas.
Elsewhere Manchester City have already won Group F. However, Napoli and Shakhtar Donetsk are still fighting it out for the other place in the knockout stages of the competition. The first legs will be played on 13, 14, 20 and 21 February, and the second legs will be played on 6, 7, 13 and 14 March 2018. From that point onwards it is a free draw so group-stage rematches and any all-Premier League clashes could be back on the agenda from that point onwards.