Amber warnings are in place across the Tayside Region until 22:00 issued by the Met Office. Exisiting yellow warnings for snow in the north of the United Kingdom for Wednesday overnight into Thursday have also been upgraded to Amber.
Friday will continue cold with sunny spells and showers, wintry showers becoming confined to northern areas by afternoon.
Forecasters said there is a chance of power cuts, while some rural communities may be cut off. After much of the country saw snow or heavy hail in the past few days, it seems as if more is on the way.
Twelve specialist snow blowers have also been prepared for use in Northern Ireland.
"That in practice means that all travel should be avoided on those parts of the trunk road affected by the amber warning, namely south and south-west Scotland for the duration of the amber warning", he said.
Scattered snow showers with slippery paths and roads are expected due to accumulations of ice on untreated surfaces.
Mountain rescue teams were drafted in to check on drivers, many of whom were stuck in their vehicles for several hours after heavy snow showers hit the area throughout Tuesday evening and into the early hours of Wednesday.
Grahame Madge from the Met Office said: "It will be another very cold night on Friday and into Saturday and this will bring further frosts and the risk of icy stretches".
The Met Office said the heaviest and most persistent snow would fall in northern England, southern Scotland and Northern Ireland overnight, with up to 20cm on higher ground.
The Pennine hilltops are covered with snow as riders make their way onto the gallops at Middleham Moor near Leyburn, as yellow snow and ice warnings are in place for northern England and Northern Ireland and much of Wales.
A status yellow warning was initially put in place for northwestern counties, however, the entire country is now being told to brace themselves for "thundersnow".
On Wednesday 17 January, winds will pick up again and temperatures will be all day around the 0 degree mark, and it may snow lightly.