However they produced an excellent first-half display with Garry Ringrose, CJ Sander and Jacob Stockdale powering over for tries, converted by Johnny Sexton to lay down the platform for victory.
After being put in space down the Ireland left, the wing chipped over Mike Brown and touched down at the second attempt, trapping the ball centimetres before it went dead.
Ireland's Grand Slam heroes including, Devin Toner, will receive a warm welcome when they return to Dublin today as expected. But thanks to England's decision to extend the pitch, the wing was able to score.
"I'm destroyed for the lads and the fans but we've seen our future", said Italy coach Conor O\Shea.
In a statement, the IRFU said: "We regret to advise that the Grand Slam Homecoming celebrations have been cancelled due to adverse weather".
Pre-tournament favourites, England finished in fifth after their worst run of Six Nations results in 12 years.
"I think that eight minutes after halftime sums up this team and this campaign", Schmidt told reporters.
"When you get to those moments it says a lot about a team - they fronted up again and again against some powerful English carriers".
"This feels more special, not only because I have started every game but also because of captaining the side", said Best. Whether we're winning or losing, we want to get better.
We have spoken about leadership density - having more leaders on the field - and that is something that is a slow burner, you have got to build that, you have got to keep working on it.
In beating England at Twickenham yesterday afternoon, Ireland have further consolidated their position as the second-best team in the world and in doing so, have closed the gap on New Zealand at the top.
"The defence was huge, we had to really fight our way out of the 22, there was a heck of a lot of character shown". "We wanted to do a Grand Slam and to do that... we'll look beyond that at a later date", he said. We owed (defence coach) Andy Farrell one.
"To do it with this group of players, coaches and management, it is really tight-knit".