Barletta was heavily favored over state Rep. Jim Christiana to become the Republican challenger for Democratic Sen.
Both parties plan to wage heavily funded campaigns in Pennsylvania in November, not only for the Senate seat but for numerous state's House districts.
A Republican who was an early backer of President Donald Trump looked to secure his party's nomination for the Senate on Tuesday in Pennsylvania, a state Democrats consider crucial for a political comeback.
That's not exactly a huge margin for Barletta, a longtime congressman who had the explicit endorsement of the President - and who spent almost $2 million on the race to just $250,000 for Christiana.
CNBC added that Casey - who's running unopposed Tuesday - is considered one of the safer senators in the group of 10, as Trump only narrowly won the Keystone State over Hillary Clinton. These results are unlikely to calm their nerves. In March, Saccone narrowly lost a U.S. House special election to Democrat Conor Lamb in the old 18th District, which overwhelmingly voted for Trump in 2016.
In an effort to challenge incumbent Democratic U.S. Sen.
Trump asked Barletta to run for U.S. Senate - the pair are on good enough terms that Barletta watched this year's Super Bowl with Trump at the Republican president's Mar-a-Lago club in Florida - and Barletta remains a staunch supporter.
"They're exhausted of the same old guard and the same cast of characters who run for reelection every year", says Christiana. Trump recorded an automated telephone message praising Barletta that was sent to voters just before the primary. "Like me, Lou Barletta is strong on the wall, tough on immigration and has already cut your taxes".
At his election night party in his hometown of Hazleton, Barletta appealed to the voters who helped Trump win the state in 2016's presidential election. "If you, like all of the others, want to keep it going this way, go out and vote for Lou".
In the hotly contested Democratic primary for the Lehigh Valley House seat being vacated by retiring Republican Rep. Charlie Dent, former Allentown solicitor Susan Wild, who was backed by EMILY's List, claimed victory.
Barletta won his House seat during the Republican midterm wave of 2010, catapulted by the attention he received while mayor of the small city of Hazleton for cracking down on immigrants in the country illegally.
Farther west in OR, incumbent Democratic Gov. Kate Brown drew a pair of primary challengers but was expected to advance to the general election. But Barletta is still far behind Casey, who has brought in more than $10 million since the beginning of the cycle.