Unveiling the campaign in Geneva, WHO Director-General Tedros Adhanom Ghebreyesus urged governments to act.
Officials think it can be done in five years because the work is well underway in many countries. It has had them for 15 years.
The WHO is pushing middle- and lower-income countries to pick up the fight, said Dr. Francesco Branca, director of the WHO's Department of Nutrition for Health and Development.
Invented at the turn of the last century, trans fatty acids are created by changing the molecular structure of vegetable oils. They say the "payoff" in improved public health outweighs the costs of using a safer oil.
There are also naturally occurring trans fats in some meats and dairy products. "Trans fat is an unnecessary toxic chemical that kills, and there's no reason people around the world should continue to be exposed".
In Denmark, the first country to mandate restrictions on industrially-produced trans fats, the trans fat content of food products declined dramatically and cardiovascular disease deaths declined more quickly than in comparable OECD countries.
Countries will likely have to use regulation or legislation to get food makers to make the switch, experts said.
The first trans fatty food to hit the USA market was Crisco shortening, which went on sale in 1911.
As per sources, numerous developed nations have already removed trans-fats from the food supply, imposing legal restrictions on packaged food.
Popularized in the 1950s, and once lionized as a healthy alternative to the saturated fats found in butter and lard, trans fats have been implicated in sudden heart attacks and strokes, but they are also associated with an increased risk for Type 2 diabetes and even infertility in women.
Switzerland, Britain, Canada, and the USA have all already moved to ban trans fats.
Quartz: How trans fat fell from grace to become a foodie villain (Purdy, 5/14).
However, according to World Health Organization, several high-income countries have virtually eliminated industrially-produced trans fats through legally imposed limits on the amount that can be contained in packaged food, or implemented nationwide bans on partially hydrogenated oils. FDA officials have not said how much progress has been made or how they will enforce their rule against food makers that don't comply.
Trans fats produced by industrial means were first introduced into the United States food supply in the 1950's and has resulted in an epidemic of heart disease.