Roy, England's second-highest run scorer in the series, sustained a deep cut to the little finger on his right hand when fielding at Lord's on Saturday and will undergo a late fitness test ahead of the third and final match at Headingley.
Morgan questioned the value of bilateral series because it can be hard to manufacture the sort of situations that can occur in tournament play.
The times have changed and India today is a two-time world cup victor and is a force to beat in world cricket. (But) having a game like this is crucial for us. I think throughout the series Dhoni hasn't batted, so this was a chance to get a knock. "Every game brings something different with significance on it".
Now in India on what is expected to be another dry, sub-continental style pitch on Tuesday, they are facing the team most likely to challenge them for that World Cup title, especially if the sun consistently shines again next year.
Vince has been flying this season for Hampshire including lifting the Royal London One Day Cup at Lord's but however well he goes today, he is unlikely to shift Roy from his opening spot long term.
While the England cricket team performed amazingly well in all the three formats of the game, the Indian batsmen failed to chase the target of 322 runs. The defeats in deciders came earlier in the development of this side, against Australia in 2015 and South Africa in 2016.
England have managed to attack him at times and the youngster faltered under pressure in the last ODI.
"They are a really strong side, as we saw in periods [at Lord's], and particularly at Trent Bridge, so to beat them in series would be quite significant - very significant". They defeated the Englishmen convincingly in the first ODI at Old Trafford by 8 wickets.
"We started better against him and the more we face him obviously the easier he got to pick".
"It takes a bit of time to get your form and your rhythm back so I'm sure the more he plays the better he'll get".