Heavy and persistent rain is due to fall from 6am until midnight on Friday in the north west of England, south west of Scotland and Lothian Borders, Wales and Yorkshire and Humber.
"Both Friday and Saturday will be wet and windy days for Shropshire, with bursts of heavy rain at times".
The Met Office is also warning of possible disruption to transport services.
Weather warnings issued from the Met Office.
The weather warning has been issued for Dublin, Louth, Wexford, Wicklow, Meath, Cork, Waterford, Donegal, Galway, Mayo, Sligo, Clare and Kerry and will remain in place from 10pm tonight until 9am on Friday.
It comes on top of existing yellow Met Office warnings for high winds and heavy rain across most of the country. Gusts 50 to 60 miles per hour are likely in some places, with potential for gusts of 70 to 80 miles per hour around exposed coasts and hills.
On Saturday, areas over high ground could see a further 50 to 80mm of rain.
The Met Office said there will be strong winds and rainfall up to 10cm, leading to possible flooding and hard driving conditions.
"Despite clearance efforts by the Council, the high winds will increase the amount of falling leaves and block drains very quickly, exacerbating flooding" he warned.
On Wednesday morning, Met Éireann issued a status orange weather warning for six counties as the storm makes its way to Ireland.
On the A83 on Tuesday, road operators said debris had been caught in one of the recently-installed landslip mitigation fences across the bottom of the slope above the road, but the carriageway had to be checked before it could reopen.
South Wales is bracing itself for a two-day deluge that's expected to cause flash floods and travel chaos. Additionally, there is a concern for storm surge, coastal flooding, and overtopping of waves around coasts, especially Atlantic coasts, due to the coinciding high spring tides.
There is also the risk of further severe Southerly winds impinging onto Southern and Eastern coastal areas during the day.