Previous research has shown that the pattern of DNA methylation in cancer cells differs from that in healthy cells.
Considering the current complicated and expensive procedure of detecting cancer and especially the delay associated with releasing the result, this new approach will make cancer detection and routine screening a simple procedure for doctors, medical experts said. In some cases, the accuracy of cancer detection runs as high as 90%. After many studies and a lot of work, scientists have come up with a universal cancer test. Additionally, the research was supported by a National Breast Cancer Foundation grant to advance cancer diagnosis testing.
As reported by the portal "Znayu" team of microbiologists from the University of John Hopkins have developed a test that detects the presence of chlamydia in 30 minutes.
Abu Sina, an AIBN researcher, stated, "Because cancer is an extremely complicated and variable disease, it has been hard to find a simple signature common to all cancers, yet distinct from healthy cells".
Sina said: "It works for tissue-derived genomic DNA and blood-derived circulating free DNA". If DNA from cancer cells is then added, it sticks to the nanoparticles in such a way that the water retains its original colour.
As part of the development of the test, the researchers found that cancer cells of breast and prostate cancer have a unique "signature" - a sample of molecules of DNA.
And so, Sina and colleagues compared the epigenetic patterns on the genomes of cancer cells to those of healthy cells, specifically focusing on patterns of methyl groups.
Specifically, the researchers looked for patterns of molecules, called methyl groups, which decorate the DNA.
So far, the University of Queensland team has tested the new technology on 200 samples across different types of human cancers, and healthy cells.
The technology has also been adapted for electrochemical systems that allow cheap and portable detection that could eventually be performed using a mobile phone. Though made of gold, the particles turn the water pink.
The team does not go as far as to say that this will be the ultimate cancer diagnostic but the technology behind it is affordable and does not require complex equipment like DNA sequencing so, while the team is humble about the results of their research, we truly want to give them a round of applause regardless. Although not precise enough to pinpoint locations, stage, or size of a tumour it would give a swift answer to whether the patient has cancer or not within a few minutes, when combined with other tests this could become a powerful diagnostic tool to determine type, location and stage. "Further clinical studies are required to evaluate the full clinic potential of the method".