His new household - the team that supports a member of the royal family - will be established this spring but the move is unlikely to happen until later in the year.
As if the Duke and Duchess of Sussex's upcoming move to Windsor and the arrival of their first child weren't enough to shake things up, their royal "court" is also undergoing a dramatic change.
However, sources with knowledge insist that this latest move has nothing to do with the reported rift and was always part of the long-term plan.
More recently, Ms Latham was a key figure in the 2016 Presidential campaign of Hillary Clinton where she was Chief of Staff to Campaign Manager John Podesta.
"The Duke of Sussex now has his own private office, which has been supporting the Duchess since the engagement of Their Royal Highnesses in November 2017", the Palace said in a statement (via Reuters).
They still have to find a new Private Secretary - the most senior role in their office - to replace Samantha Cohen who will leave in the summer.
Meghan's female bodyguard was next to quit and now her private secretary Amy Pickerill is stepping down.
Jason Knauf and Christian Jones, who have worked for the couple for the past year, will continue to work exclusively for The Duke and Duchess of Cambridge.
Kensington Palace will support the Sussexes until their new staffing arrangements are in place.
It appears that numerous most senior staff, now at Kensington Palace, are staying to work with the Cambridges.
Christian Jones, on the other hand, has been appointed as Communications Secretary to William and Kate.
Fans are also betting the baby will be named after Harry's mother.
It's a reflection of the new role Harry has in the Royal Family as a married man and a soon-to-be father. The baby will be seventh in line to the British throne after Prince Charles, Prince William and his three children and Prince Harry.